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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease li-fraumeni syndrome
Comorbidity C0007113|rectal carcinoma
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PubMedID- 26449693 Analysis of k-ras codon 12 and tp53 mutations in patients with advanced colorectal carcinoma.
PubMedID- 21513535 Bazan and co-workers (2005) reported that in sporadic colorectal carcinoma tumours with tp53 mutations in l3 domain are associated with a worse prognosis (as judged by disease free time only) than other tumours [31].

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